FCPS PART-1 (PAPER I) SYLLABUS

 

ANATOMY

1. General Gross Anatomy (General Outline)
– Muscles
– Joints
-Major Blood Vessels

2. Embryology (General aspects)
– Histology (General)
– Types of tissues
– Epithelia
– Muscles
– Nerve
– Blood Vessels
– Fibro fatty tissue
– Lymph Nodes

3. Brain and Spinal Cord
– Gross Structure
– Spinal Nerves (Origin and distribution)
– Cranial Nerves

4. Head and Neck – General Aspects

5. Viscera: Gross Structure
– Heart
– Lung
– Kidney

6. Anatomical Outline
– Bronchial Tree

7. Endocrine Glands – Anatomical Structure
– Pituitary, Thyroid, Parathyroid and Adrenal Glands

2. PHYSIOLOGY, PHARMACOLOGY & BIOCHEMISTRY

1. General Physiology

• Components of cell and cytoplasm with their functions (in general) & transport across cell membranes.
• Nerves and Muscle Contraction
• Classification and properties of nerve fibers
• Receptors (types, properties & functions)
• Function of motor and sensory areas of Brain.
• Cerebrospinal Fluid (CSF), it’s formation, functions, drainage, lumbar puncture
• Autonomic nervous system (outflow and responses of affected organs)
• General properties and composition of blood
• Normal counts and functions of RBCs, WBCs, Platelets
• Mechanism of homeostatic coagulation factors and their actions
• Blood groups (types, antigens, antibodies, phenotypes, genotypes and significance)
• Conducting tissues of heart (generation and propagation of cardiac impulse).
• Cardiac cycle (pressure, volumes, valvular changes)
• Blood pressure and its regulation (general)
• Respiratory and non-respiratory functions of respiratory tract
• Body fluids, compartments and regulations of Osmotic equilibrium and acid base balance.
• Regulation of ECF and blood volume
• General functions of kidney
• Regulations of body temperature

2. Pharmacology

• General principles of rational drug therapy
• Clinical pharmacokinetics
• Adverse reactions of common drugs

3. Biochemistry

• Requisites of a balanced diet
• General principles of electrolyte balance
• Role and function of endocrine hormones
• Metabolism of carbohydrates, protein, fats and vitamins

3. PATHOLOGY INCLUDING MICROBIOLOGY

• Effects of injury on cell by physical, chemical and biological agents
• Inflammation (Acute & Chronic Including granulomatous)
• Regeneration and repair
• Metabolic response to trauma
• Disturbance of homeostatic mechanism (hemorrhage and shock and Oedema)
• Thrombosis and embolism, infarction and gangrene
• Disorders of growth (adaptation, atrophy, hypertrophy, hyperplasia)
• Carcinogens and pre-malignant lesions
• Neoplasia: General classification and its spread
• General aspects of tumor markers
• General characteristics of bacteria, viruses, chlamydia, recketsia, parasites and fungi
• Immunology and Immune system: General principles
• Medical genetics – basic concepts
• Interpretation of routine biochemical tests e.g liver function test, glucose, urea and creatinine.
• Nutritional diseases: deficiency of vitamins and minerals

4. RESEARCH AND BIOSTATISTICS – BASIC CONCEPTS EPIDEMIOLOGY

• An introduction to epidemiology and its role in understanding distribution and determinants of disease.
• Measure of disease occurrence
• Screening

Biostatistics:

• Introduction to biostatistics
• Data and its kinds
• Summarization of data
• Normal distribution
• Point and interval estimation and probability
•  Hypothesis testing, significance level and power

 

5. BEHAVIORAL SCIENCE AND MEDICAL ETHICS – GENERAL PRINCIPLES

• Medical Ethics
• Communication skills including doctor patient relationship and counseling
• Psycho social aspects of general healthcare

 

Medicine & Allied (FCPS PART I) PAPER II SYLLABUS

 

ANATOMY/HISTOLOGY / EMBRYOLOGY

Embryology

• Development ol C.V.S.. Brain. Kidney
• Common doveopmontal dolocts

Histology

• Liver Pancreas Spleen
• Kidney
• Brain
• G.l.T

Regional Anatomy

Structure and General disposition

Upper Limb:

• Pectoral girdle and axilla
• Breast
• Arm
• Forearm
• Wrist
• Hand
• Innervation of muscles
• Osteology

Lower Limb:

• Gluteal region and hip joint
• Thigh
• Popliteal (ossa and knee joint, log
• Ankle and Fool
• Innervation ol muscles
• Osteology

Thorax:

• Thoracic wall and diaphragm
  • Heart
  • Mediastinum
  • Pleura
  • Lungs

Abdomen:

• Anterior abdominal wall
  • Peritoneum
  • Gastro Intestinal tract
  • Liver and biliary tract
  • Poncroos
  • Sploen
  • Kidney
  • Ureters
  • Suprarenal gland

Pelvis:

• Pelvic cavity
  • Urinary bladder
  • Male genital organs and urethra
  • Female genital organs
  • Pelvic vessels
  • Nerves
  • Pelvic joint and ligaments
  • Lumber and sacral plexuses

Head. Neck, Spine:

• Cranial cavity and meninges
• Vertebral column and vertebral canal
• Scalp
• Face Parotid glands
• Nose and sinuses
• Oral cavity
• Pharynx

Central Nervous System:

• Cerebrum – Internal structure
• Cortical areas
• Cerebellum
• Brain stem
• Descending and Ascending tracts
• Special senses – Anatomical pathway, Visual, Taste, Olfactory
• Autonomic Nervous System

PHYSIOLOGY & BIOCHEMISTRY

       Kidney:

• Functions of kidney
• Glomerular filtration – determinants
• Tubular reabsorption and secretion
• Regulation of Sodium. Potassium,
• Calcium. Phosphate and Magnesium concentration
• Micturition

       The Heart:

• Physiology of cardiac muscle
• Cardiac cycle
• Relationship of tho hoart sound to heart pumping, cardiac output
• Electrical Activity of the Heart
• Electro cardiogram – characterislics
• Vectorial analysis of E.C.G.- Abnormalities
• Cardiac Arrhythmias

       The Circulation:

• Capillary fluid exchange
• interstitial fluid and lymph flow
• Nervous Regulation of the circulation
• Control of blood pressure
• Humoral control of circulation
• Circulation through special regions – Cerebral. Coronary, Pulmonary & splanchnic
• Cardiovascular changes in exercise

Gastro Intestinal System:

• Motility and propulsion – Nervous Contracions
• Secretory function
• Digestion and absorption • Malabsorption syndrome
• Functions of liver – Metabolic functions
• Bilirubin formation and excretion – types of Jaundice
• Energy Metabolism • Energy requirement
• Defecation
• Vomiting

Respiratory System:

• Pulmonary Ventilation: Ventilation – Perfuse ratio
• Principles of gas exchange diffusion of gases
• Pulmonary Capillary dynamics
• Regulation of respiration. Lung function tests
• Respiratory insufficiency
• Hypoxia
• Cyanosis
• Oxygen therapy
• Hypercapnia. Hypercapnia
• Respiratory changes in exercise

Central Nervous System:

• Cortical and brain stem control of motor functions.
• Cerebellum – Functions in overall motor control
• Basal ganglia • Functions in executing pattern of motor activity
• Role in cognitive control of sequence ot motor control:
  • Integration of total motor control systems
  • Control of posture and movement
  • Cerebral cortex – higher functions of the Nervous system:
    • Conditioned reflexes
    • Learning and Memory
    • Function of Neocortex
• The limbic system and the hypothalamus:

Behavioural and Motivational Mechanism

• Physiology of sleep and electric activity of the brain • E.E.G.
• Somatic sensations • pain, headache, thermal sensation.
• Speech mechanism.

Physiology of special senses:

• Smell
• Taste
• Hearing Vision

Physiology of Endocrine:

• Mechanism of action of Hormones
• Pituitary Hormones • Hypothalamic control, growth hormone. ADH. oxytocin
• Adrenal glands – Adrenocortical hormones- functions and control of secretion
• Adrenal Medullary Hormones
• Thyroid Metabolic Hormones – Functions and control of secretion
• Parathyroid Hormone – Calcium and Phosphate Regulation
• Vit. D for development of bone and teeth.
• Insulin, glucagon.
• Reproductive System.
• Male reproduction.
• Fomalo Hormones, Hypothalamic-pituitary and ovarian control of reproduction.
• Pregnancy and lactation.
• Neonatal physiology

PATHOLOGY/MICROBIOLOGY / IMMUNOLOGY

Mechanism of immune mediated injury:

• Types of hyper-sensitivity reactions

Mechanism of auto-immune diseases:

• Immunologic tolerance
• Genetic factors in auto immunity
• Major abnormalities of immune function m AIDS

Immuno-deficiency Diseases:

• Primary immuno-deficiencies
• Severe combined immunodeficiency
• Genetic deficiencies of complement components
• Secondary immuno- deficiencies

Neoplasia:

• Epidemiology
• Etiological factors
• Tumor Immunity-Host defense against tumour
• Effects of tumor on Host
• Para neoplastic syndrome
• Grading and staging of malignancy
• Laboratory diagnosis of cancer

Genetic Diseases:

• Transmission Pattern of single gene disorders
• Disorders of mufti-factorial inheritance
• Cytogenetic disorders involving autosome and sex chromosome
• Single gene disorders with atypical pattern of inheritance
• Diagnosis of genetic disease
• Factors responsible for common environmental diseases
• Pathogenesis of Atherosclerosis and Ischaemic Heart Disease – Risk factors

Disorders of Haemopoietic and lymphoid systems:

• Non-neoplastic disorders of W B C
• Bleeding disorders • causes.

Pathophysiology of Jaundice

Myco-bacteria

• Tuberculosis
• Leprosy

Viruses

• Pathogenesis and diagnosis of viral diseases
• Hepatitis • A.B.C.D.E
• HIV /AIDS
• Rabies
• Herpes
• Influenza

Parasitology:

• Haemo-parasites • Malaria. Leishmania, filariasis
• Intestinal – Giardia. entamoeba, nematodes, cestodes
• . Hydatid disease

PHARMACOLOGY

Antibiotics. Antifungal and Anti-Viral Drugs:

• Anti-tubercular drugs
• Anti-Malarial
• Anti-Amebic
• Anti-helmintic

Drugs used in peptic ulcer:

• Anti-emetics
• Purgatives
• Gastric anti-acid
• Drugs used in diarrhea

Analgesics – NSAIDs:

• Anti-rheumatic and anti-gout drugs
• Opioid analgesics

Drugs used in Parkinsonism

Drugs used in epilepsy

Anxiolytics and hypnotics

Anti-depressants

Anti-histamines (Hi Blockers)

Anti-hypertensive drugs Anti-anginal drugs

Drugs used in congestive heart failure and arrhythmias

Drugs used in hyper-lipidemia

Drugs used in anemias

Drugs used in coagulation disorders

Insulins and oral anti-diabetics

Thyroid and anti-thyroid drugs

Autonomic drugs

Vaccine and immuno-globullns

Subject	Preferred Book
Anatomy	Snell Review Anatomy
Physiology	First Aid Step 1 & BRS Physiology (without Neurology)
Biochemistry	First Aid Step 1  + Past MCQs
General Pathology	First Aid Step 1 (Tables) + Pathoma/BRS Pathology
Special Pathology	First Aid Step 1 Special Pathology (complete) + Pathoma (optional)
Microbiology	First Aid Step 1
Immunology	First Aid Step 1 + BRS Pathology
Neurology	Snell Neuroanatomy/Kaplan Neuroanatomy
Embryology	High yield Embryology + First Aid Tables + Theory in Tanveer notes
Histology	First Aid + Tanveer Notes
Community Medicine	First Aid + Tanveer Notes
Pearl Point Book	SK Notes or Rafiullah Notes or Double A Notes
Select only one MCQ Book	Medicall or Salahudin Kamal or Rabia Ali or Double A Notes